Showing posts with label weight loss. Show all posts
Showing posts with label weight loss. Show all posts

Tuesday, September 11, 2012

Intermittent fasting

Improvements in coronary heart disease risk indicators by alternate-day fasting involve adipose tissue modulations.
http://www.ncbi.nlm.nih.gov/pubmed/20300080
16 obese subjects instituted an alternate-day fasting program (eat for 24 hours, then fast for 24 hours). Subjects lost Body weight (average loss: 5.7 +/- 0.9 kg) but not Lean body mass. They had lower LDL cholesterol levels & reduced Waist circumference.

Alternate-day fasting and chronic disease prevention: a review of human and animal trials.
www.ncbi.nlm.nih.gov/pubmed/17616757
Human trials support beneficial effects on HDL & Triglycerides. Animal studies support beneficial effects on Diabetes incidence, Cancer, fasting Blood glucose, Insulin concentrations, Total cholesterol, Blood pressure, & response to Myocardial infarction (Heart attack).

Saturday, July 28, 2012

Vitamin D, Testosterone, & Coffee

Vitamin D increases Testosterone levels
http://www.ncbi.nlm.nih.gov/pubmed/21154195 - 54 overweight, non-diabetic men with deficient Vitamin D levels (<50 nmol/L) undergoing a weight reduction program were randomized to ~3000IU Vitamin D daily for 1 year or Placebo. Vitamin D levels increased by ~50 nmol/L & Total testosterone levels increased by ~11 to 13 nmol/L in the Treatment group, with no change seen in the Placebo group.

For reference, hormone therapy is usually started for men with Total testosterone < ~12 nmol/L.

Testosterone improves Metabolic syndrome
http://www.medscape.com/viewarticle/755673 -147 men with Total testosterone levels <~12 nmol/L were given 1000 mg Testosterone undecanoate injections every 3 months for at least 4 years. The average waist reduction was 8 cm; average weight loss was 12.9 kg. During the 1st year of treatment the average Lean body mass increase was 4.5 - 5 kg & average Fat loss was 5 to 6 kg. Total cholesterol, LDL, & Triglycerides were all significantly reduced; C-reactive protein levels (a marker of Inflammation) dropped from 7.1 to 1.6 mg/L.


Testosterone aids Weight loss & Waist-size reduction

http://www.medscape.com/viewarticle/767696 -130 men with Total testosterone levels <~12 nmol/L were given 1000mg Testosterone undecanoate injections on Day 1, 6 weeks later, then every 3 months. Average weight loss was 14.3 kg; average waist reduction was 11 cm.

Coffee may help prevent Atherosclerosis (hardening of the arteries)
http://www.ajcn.org/content/86/3/604.long - 10 healthy volunteers were given 200mL of Filtered coffee after an overnight fast; researchers measured the resistance of the volunteers' LDL to oxidation; LDL had increased resistance to oxidation, presumably due to increased incorporation of Phenolic acids (found in the Coffee) within the LDL particles.

Oxidation of LDL is considered to be a major initiating factor in the development of Atherosclerosis (hardening of the arteries), as can be read about here.